EPA Releases New IRIS Program Outlook Document

The Integrated Risk Information System (IRIS) is a key health assessment program developed by the U.S. Environmental Protection Agency (EPA). Originating in 1985, IRIS is focused on providing a source of information related to effects on health from environmental contaminant exposure. The IRIS Program Outlook document, typically released triannually, offers an updated outlook of activities for the program relative to particular chemical substances. It also facilitates communication of relevant information to the Agency by interested parties.

October 2022 IRIS Program Outlook

For the October 2022 IRIS Program Outlook, a listing of the corresponding chemical substances and the recent assessments in development for them are displayed in the table below.

Substance NameCAS NumberProgram StatusRecent Assessment Materials
Arsenic, Inorganic7440-38-2Step 2Updated Problem Formulation and Systematic Review Protocol for the IRIS inorganic Arsenic Assessment [2019]
Chloroform67-66-3Step 1Systematic Review Protocol for the IRIS Chloroform Assessment (Inhalation) [2018]
Chromium VI18540-29-9Step 4IRIS Toxicological Review of Hexavalent Chromium [2022]
Ethylbenzene100-41-4Step 1IRIS Assessment Plan for Ethylbenzene [2017]
Formaldehyde (Inhalation)50-00-0Step 4IRIS Toxicological Review of Formaldehyde-Inhalation [2022]
Mercury Salts, InorganicVariousStep 1Systematic Review Protocol for the Inorganic Mercury Salts IRIS Assessment [2021]
Methylmercury22967-92-6Step 1Systematic Review Protocol for the Methylmercury IRIS Assessment [2020]
Naphthalene91-20-3Step 1IRIS Assessment Plan for Naphthalene [2018]
Perfluorobutanoic Acid (PFBA)375-22-4Step 6IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts [2021]
Perfluorodecanoic Acid (PFDA)335-76-2Step 3Systematic Review Protocol for the Perfluorodecanoic Acid (PFDA) IRIS Assessments [2019]
Perfluorohexanesulfonic Acid (PFHxS)355-46-4Step 1Systematic Review Protocol for the Perfluorohexanesulfonic Acid (PFHxS) IRIS Assessment [2019]
Perfluorohexanoic Acid (PFHxA)307-24-4Step 5IRIS Toxicological Review of Perfluorohexanoic Acid (PFHxA) and Related Salts [2022]
Perfluorononanoic Acid (PFNA)375-95-1Step 1Systematic Review Protocol for the Perfluorononanoic Acid (PFNA) IRIS Assessment [2019]
Polychlorinated Biphenyls1336-36-3Step 1Systematic Review Protocol for the Polychlorinated Biphenyls (PCBs) Noncancer IRIS Assessment [2019]
Uranium, natural7440-61-1Step 1IRIS Assessment Plan for Uranium (Oral Reference Dose) [2018]
Vanadium and Compounds (Oral)VariousStep 1Systematic Review Protocol for the Vanadium and Compounds (Oral Exposure) IRIS Assessment [2021]
Vanadium and Compounds (Inhalation)VariousStep 1IRIS Assessment Plan for Inhalation Exposure to Vanadium and Compounds [2021]

Source: U.S. Environmental Protection Agency

More Information

More information regarding IRIS and the IRIS Program Outlook may be found on the EPA’s website. Additionally, you can visit the ToxPlanet website and blog regularly for information on new developments.

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